Operator Protection
Product Protection
Environmental Protection
Clean Air
Cytoculture® Cytotoxic Safety Cabinet (CYT)
Esco’s Cytoculture® Cytotoxic Safety Cabinet is the premium solution for cytotoxic/antineoplastic drug processing; providing the highest level of patient, operator and environmental protection. This revolutionary product builds on Esco’s experience of more than 20 years as a global leader in biological safety containment technology.
The unique demands of handling and preparing cytotoxic drugs for chemotherapy use require a specialized cabinet. As cytotoxic drugs cannot be inactivated by chemical decontamination, Class II biosafety cabinets should not be used.
Key Benefits:
Safe filter changing
Safer dual exhaust filters
HEPA certified to EN 12469
Sentinel™ Silver Microprocessor controller supervises all functions.
Meets the requirements of the European Std. EN 12469 for microbiological safety cabinets.
Provides you with the highest level of operator safety to protect you and your personnel from the hazardous compounds used in cytotoxic drugs.
Motorized sash helps simplify transfer of materials into the work zone.
Highest level of protection within the work zone for patient safety and product cleanliness.
Esco Isocide™ antimicrobial coating on all painted surfaces.
Dual long-life HEPA filters for supply and exhaust airflow.
Additional secondary HEPA exhaust filter.
Spacious knee room maximizes operator comfort, 245mm (9.6") inward
Available in 1.2 and 1.8 m models (4' and 6').
Air enters the cabinet through perforations located along the front of the work zone before mixing with used downflow air in a common chamber below the work zone (this inflow air does not mix with the filtered downflow air in the cabinet's main chamber). The mixed air then passes through the HEPA filter located beneath the work zone.
The HEPA filtered air then passes through internal ducting in the back wall of the cabinet to a common air plenum where 35% is exhausted through the HEPA exhaust filter and 65% is forced evenly through the HEPA supply filter. This sterilized air then passes through the main chamber as downflow air, flushing all contaminates from the work zone.
At the work surface the downflow airstream splits and enters the common air chamber beneath the work zone through perforations located at the front and back of the main chamber, from where the cycle is repeated.
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Guide to Models |
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CYT - __ A __ |
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Cabinet |
Code |
Nominal Width |
Code |
Electrical Code |
Code |
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Cytoculture® Cytotoxic Safety Cabinet |
CYT |
4 ft (1.2 m) |
4 |
220-240 V, AC, 50 Hz, 1Ø |
1 |
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6 ft (1.8 m) |
6 |
110-120 V, AC, 50 Hz, 1Ø |
2 |
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220-240 V, AC, 60 Hz, 1Ø |
3 |
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General Specifications,
Cytotoxic Safety Cabinets |
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Note to customer: Insert
electrical voltage number into last model number digit _ when ordering |
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Cytoculture® Cytotoxic Safety Cabinet |
CYT-4A_ |
CYT-6A |
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Nominal Size |
1.2 meters (4') |
1.8 meters (6') |
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External Dimensions (W x D x H) |
1420 x 846 x 2190 mm (55.9"
x 33.3" x 86.2") |
2030 x 846 x 2320 mm (79.9"
x 33.3" x 91.3") |
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Internal Work Area Dimensions (W x D x H) |
1264 x 620 x 670 mm (49.8" x
24.4" x 26.4") |
1870 x 620 x 670 mm (73.6" x
24.4" x 26.4") |
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Usable Work Area |
0.60 m2 (6.4 sq.ft.) |
0.90 m2 (9.7 sq.ft.) |
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Tested Opening |
203 mm (8.0") |
203 mm (8.0") |
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Maximum Sash Opening |
440 mm |
440 mm |
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Average Airflow Velocity |
Inflow |
0.45 m/s (90 fpm) |
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Downflow |
0.30 m/s (60 fpm) |
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Exhaust Volume with Ducting |
Inflow |
0.45 m/s (90 fpm) |
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Downflow |
0.30 m/s (60 fpm) |
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CBV Exhaust Volume |
611 m3 / h (360 cfm) |
931 m3 / h (548 cfm) |
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Static Pressure at CBV Exhaust Volume |
39 Pa / 0.15 in H2O |
63 Pa / 0.25 in H2O |
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Filter Typical Efficiency |
Downflow |
>99.995% at 0.1 to 0.3 micron,
ULPA as per IEST-RP-CC001.3 USA >99.995% at MPPS, H14 as per
EN 1822 EU |
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Exhaust |
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V-bank Filter Typical Efficiency |
Exhaust |
>99.995% at 0.1 to 0.3 micron,
ULPA as per IEST-RP-CC001.3 USA >99.995% at MPPS, H14 as per
EN 1822 EU |
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Sound Emission per EN 12469* |
61 dBA |
63 dBA |
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LED Lamp Intensity at Zero ambient |
>1300 Lux (>121 foot
candles) |
>1000 Lux (>93 foot
candles) |
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Cabinet Construction |
External |
1.5 mm (0.06") 16 gauge
electrogalvanized steel with Isocide white oven-baked epoxy powder-coating |
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Internal |
Stainless steel Type 304 with
No.4 finish, 1.5 mm (0.06") / 16 gauge thick |
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Electrical** |
220-240V, AC, 50 Hz, 1Ø |
CYT-4A1 |
CYT-6A1 |
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Cabinet Full Load Amps (FLA) |
8A |
9A |
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Optional Outlets FLA |
5A |
5A |
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Cabinet Nominal Power |
429W |
568W |
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Cabinet BTU |
1464 BTU/hr |
1938 BTU/hr |
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110-120V, AC, 60 Hz, 1Ø |
CYT-4A2 |
CYT-6A2 |
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Cabinet Full Load Amps (FLA) |
11A |
11.5A |
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Optional Outlets FLA |
5A |
5A |
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Cabinet Nominal Power |
653W |
793W |
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Cabinet BTU |
2228 BTU/hr |
2706 BTU/hr |
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220-240V, AC, 60 Hz, 1Ø |
CYT-4A3 |
CYT-6A3 |
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Cabinet Full Load Amps (FLA) |
9A |
9.5A |
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Optional Outlets FLA |
5A |
5A |
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Cabinet Nominal Power |
549W |
778W |
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Cabinet BTU |
1873 BTU/hr |
2655 BTU/hr |
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Net Weight |
383 kg (844 lbs) |
500 kg (1102 lbs) |
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Shipping Weight |
415 kg (915 lbs) |
578 kg (1274 lbs) |
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Shipping Dimensions, Maximum (W x D x H) |
1560 x 930 x 2230 mm (61.4” x 36.6” x 87.8”) |
2170 x 930 x 2230 mm (85.4” x 36.6” x 87.8”) |
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Shipping Volume, Maximum |
3.26 m3 (115 ft3
) |
4.49 m3 (158.6 ft3
) |
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* Noise as measured in open field / anechoic chamber.
** Additional voltages may be available; contact Esco for ordering information.
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Accessories for Cytoculture®
Cytotoxic Safety Cabinets |
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Models |
CYT-4A |
CYT-6A |
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Exhaust Ducting |
Anti-blowback Valve |
ABBV-10P (5170352) |
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Manual Volumetric Exhaust
Damper |
B2-Damper (5170104) |
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Thimble Exhaust Collar (10
inches diameter) |
ECO-LA24-Mk3-LH (5170099) |
ECO-LA26-Mk3-LH (5170102) |
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Work Zone |
UV Lamp |
UV-30A (5170255) |
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IV Bar |
IV-1260 (5170277) |
IV-1870 (5170279) |
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Electrical Outlet |
Direct Mounted Electrical
Outlet - Plug Code |
EO-H |
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Service Fixtures |
EU SF - Gas - 40 mm |
SF-1G40 (5170002) |
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EU SF - Vacuum - 40 mm |
SF-1V40 (5170003) |
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EU SF - Nitrogen - 40 mm |
SF-1N40 (5170011) |
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EU SF - Air - 40 mm |
SF-1A40 (5170006) |
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EU SF - Water - 40 mm |
SF-1W40 (5170017) |
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American Style Service Fixture
- Universal - 40 mm |
SF-2U40 (5170018) |
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Copper Piping for Service
Fixture (Must be Factory Installed) |
CU-Pipe (5170026) |
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Carbon Filter Options |
CYT-001 (5080008) |
CYT-002 (5080009) |
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Misc |
Solenoid Valve Fitting |
SL-Valve (5070086) |
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IQ/OQ Protocol |
9010179 |
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Removable Granite Slab with
SS304 Platform |
5260310 |
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Note: For other customizations and
accessories, please contact Esco.
