Operator Protection
Product Protection
Environmental Protection
Clean Air
Streamline® Containment Isolator - Class III
The Streamline® Containment Isolator Class III (SCI Class III) configuration solely operates in a negative pressure, with its on-board fan providing -37 Pa to -125 Pa (max) in the process chamber and -25 Pa to -75 Pa (max) in the pass-through chamber.
"To comply fully with biosafety standards, the unit must be ducted to the building exhaust to meet negative pressure BSL-3 requirements."It provides an ISO Class 5 unidirectional total exhaust airflow, ensuring the sterility of the work zone during the whole manufacturing process. It is also equipped with double exhaust HEPA filters via Bag-In, Bag-Out (BIBO) system to prevent untoward exposure during filter change procedures. It has an option to place one (1) dunk at the side of the work zone (external).
Plug and Play! For clients or facilities that do not have the capacity to provide a 100% ducting system, the SCI Class III and its optional feature for an integrated enhanced blower exhaust module system, can easily achieve a pressure of up to -125Pa.
Key Benefits:
Complies with the international cGMP standards
Class 3 pressure tested as per ISO 10648-2
ISO Class 5 air cleanliness as per ISO 14644-1
Fast purging time
Compliant to USP <797> <800>
ULPA filters (as per IEST-RP-CC001.3 and HEPA (H14) filter as per EN 1822) with a typical efficiency of >99.999% at 0.1 to 0.3 microns, providing ISO Class 3 air cleanliness as per ISO 14644-1
FDA-grade pressure-tight static seals
Sentinel™ Gold microprocessor controller supervises all functions and monitors airflow and pressure in real-time
Robust dual-wall construction. Unique Esco Dynamic Chamber™ plenum surrounds filter seals with negative pressure
Safe-change cuff rings permit hypalon sleeve changes with zero risk of work zone or environment contamination
Total Exhaust
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Ambient air is pulled through the inlet pre and main filter via the main fans at the top of the isolator. This creates positive pressure on the plenum which provides the downflow of air with a velocity of 0.40 m/s ± 20%.
The pre-filter extends the life of the filters by trapping larger particulates that can easily clog the main filters
This downflow supply then provides an ISO Class 5 environment and unidirectional airflow inside the isolator; thus, protecting the materials inside the main chamber and pass-through.
Air from the work zone and pass-through is then quickly purged by the fans to keep the area clean. The purge is completely exhausted through HEPA filters as well; ensuring that only clean air is exhausted back to the environment.
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Isolator Class III Models |
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SCI-2GC8-N3SL-III |
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Isolator Unit |
Model |
No. of gloves - Nominal Width |
Glove port design |
Electrical Requirements |
Pressure |
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Streamline® Containment Isolator |
SCI |
2G |
5 ft (1.6m) |
C |
Circular glove port |
8 |
220-240 V AC, 50/60Hz, 1Ø |
N3 |
Process zone: Pass -through zone: *For units with integrated exhaust blower module, If a higher negative pressure is needed to meet other local BSL standards, the unit must be linked to external blower or building exhaust. |
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3G |
6 ft (1.95m) |
O |
Oval glove port |
9 |
110-120 V AC, 50/60Hz, 1Ø |
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To avail dunk tank option MUST INDICATE CLEARLY in PO: 1: With dunk tank 0: Without dunk tank |
Upon ordering, input material of construction at the end of the model code: SCI-2GC_-N3SL-III-SS or -EG ••- SS: Full stainless steel exterior •• -EG: Electrogalvanized steel with ISOCIDE™ coating |
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Standard Accessories
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Electromagnetic interlocking doors to prevent cross-contamination
Foot switch included to easily open the inner doors
Single-piece or multi-piece stainless steel 316L work top
Energy efficient LED lighting with higher durability and better quality
Electrical Outlets and Utility Fittings
Electrical outlet, ground fault, North America
Electrical outlet, Euro/Worldwide
Support Stands
Fixed height, available 711 mm (28") or 864 mm (34") - With levelling feet, ± 38.1 mm (1.5") (SAL) - With casters (SPC)
Telescoping height stand for levelling feet (STL), nominal range 660 mm to 960 mm (26"to 37.8")
Telescoping height stand for casters (STC), nominal range 660 mm to 880 mm (26" to 34.6") - Adjustable in 25.4 mm (1") increments
Infinitely adjustable hydraulic stand with casters elevates to accommodate a sitting or a standing user’s work surface height (SHM)
Support Stands
A 4-glove port (4G) design is possible by combining two units of 2-glove port (2G) isolators, interconnected by a vertical non-interlocking door; with two pass-through chambers.
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External material of construction:
Electrogalvanized steel with ISOCIDE™ powder coating
Stainless steel 304
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Dunk tank
One dunk tank below the work zone
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Exhaust types
Double HEPA exhaust filter (BIBO top and non-BIBO bottom)
Side Exhaust Connection (for TE units)
*Note: Additional carbon filter is available as an option for all exhaust filter configurations
IV bar, with hooks
UV lamp
Flexible / Thimble exhaust collar
Side Exhaust Connection (for TE units)
Hard ducting with Anti-blowback valve
Perforated shelf to increase work zone space
Cleaning accessories
Alarm package
Laboratory cart
Adjustable foot rest
Stainless steel turntable
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Butterfly valve:
Manual
Automatic
Add-Ons
Monitor System
Mounted on the rear of the isolator
Beside the front panel; equipped with a keyboard and mouse arm
Mobile BioVap™ biodecontamination system
Glove Leak Tester
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Automated pressure hold testing (APHT)
With on-board compressed air
with on-board pump
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CCTV integration
Back wall
Front of the visor with a stainless steel mount
Back-up battery for the electromagnetic interlocks (contact Esco for more information)
Side-syringe pass-through chamber
