Streamline® Containment Isolator - Class III

The Streamline® Containment Isolator Class III (SCI Class III) configuration solely operates in a negative pressure, with its on-board fan providing -37 Pa to -125 Pa (max) in the process chamber and -25 Pa to -75 Pa (max) in the pass-through chamber.

"To comply fully with biosafety standards, the unit must be ducted to the building exhaust to meet negative pressure BSL-III requirements."

It provides an ISO Class 5 unidirectional total exhaust airflow, ensuring the sterility of the work zone during the whole manufacturing process. It is also equipped with double exhaust HEPA filters via Bag-In, Bag-Out (BIBO) system to prevent untoward exposure during filter change procedures.

Key Benefits:

World’s most certified Class III Isolator BSC. Compliant to all international biosafety standards.
Class 3 pressure tested as per ISO 10648-2
ISO Class 5 air cleanliness as per ISO 14644-1
Fast purging time
Extreme negative pressure up to -125 Pa in Process Chamber, enhancing operator and environment protection

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Features

ULPA filters (as per IEST-RP-CC001.3 and HEPA (H14) filter as per EN 1822) with a typical efficiency of >99.995% at 0.1 to 0.3 microns, providing ISO Class 3 air cleanliness as per ISO 14644-1
FDA-grade pressure-tight static seals
Sentinel™ Gold microprocessor controller supervises all functions and monitors airflow and pressure in real-time
Robust dual-wall construction. Unique Esco Dynamic Chamber™ plenum surrounds filter seals with negative pressure
Safe-change cuff rings permit hypalon sleeve changes with zero risk of work zone or environment contamination

Principle

Total Exhaust

Ambient air is pulled through the inlet pre-filter and main filter via the main fans at the top of the isolator. This creates positive pressure on the plenum which provides the downflow of air with a velocity of 0.40 m/s ± 20%.
- The pre-filter extends the life of the filters by trapping larger particulates that can easily clog the main filters
This downflow supply then provides an ISO Class 5 environment and unidirectional airflow inside the isolator; thus, protecting the materials inside the main chamber and pass-through.
Air from the work zone and pass-through is then quickly purged by the fans to keep the area clean. The purge is completely exhausted through HEPA filters as well; ensuring that only clean air is exhausted back to the environment.

Models

Guide to Isolator Class III Models
SCI-2G8-N3SL-III-EG
Isolator Unit	Model	No. of gloves - Nominal Width		Electrical Requirements		Code		External Construction
Streamline® Compounding Isolator (SCI)	SCI	2G	5 ft (1.6m)	8	220-240 V AC, 50/60Hz, 1Ø	N3	Process zone: -125 Pa	EG – Electrogalvanized Steel
		3G	6 ft (1.95m)	9	110-120 V AC, 50/60Hz, 1Ø		Pass-through zone: -75 Pa	SS – Stainless Steel 304

Upon ordering, input material of construction at the end of the model code: SCI-2G_-N3SL-III-SS or EG

SS: Full SS 304 stainless steel exterior
EG: Electrogalvanized steel with ISOCIDE™ coating

Accessories

Standard Accessories

Electromagnetic interlocking doors to prevent cross-contamination
- Foot switch included to easily open the inner doors
Single-piece or multi-piece stainless steel 316L work top
Energy efficient LED lighting with higher durability and better quality

Electrical Outlets and Utility Fittings

Electrical outlet, ground fault, North America
Electrical outlet, Euro/Worldwide

Support Stands

Fixed height, available 711 mm (28") or 864 mm (34") - With levelling feet, ± 38.1 mm (1.5") (SAL) - With casters (SPC)
Telescoping height stand for levelling feet (STL), nominal range 660 mm to 960 mm (26"to 37.8")
Telescoping height stand for casters (STC), nominal range 660 mm to 880 mm (26" to 34.6") - Adjustable in 25.4 mm (1") increments
Infinitely adjustable hydraulic stand with casters elevates to accommodate a sitting or a standing user’s work surface height (SHM)

Other Accessories

External material of construction:
- Electrogalvanized steel with ISOCIDE™ powder coating
- Stainless steel 304
Carbon Filter
IV bar, with hooks
UV lamp
Manual Latches
Manual Volumetric Damper
Top Exhaust collar
Side Exhaust Connection
Anti-blowback valve
Perforated shelf to increase work zone space
Alarm package
Adjustable foot rest
Monitor System
- Mounted on the rear of the isolator
- Beside the front panel; equipped with a keyboard and mouse arm

Glove Leak Tester
Automated pressure hold testing (APHT)
- With Mobile Compressor
- Without Mobile Compressor
CCTV integration
- On the side of the process chamber with acrylic viewing panel
Back-up battery for the electromagnetic interlocks (contact Esco for more information)