Operator Protection
Product Protection
Environmental Protection
Clean Air
Dynamic Passboxes / Dynamic Floor Laminar Hatches (DPB/DFLH)
Esco DPB/DFLH is an aseptic architectural system used to prevent contaminants interfering with the clean suites. It is utilized for transfer of materials into and out of the critical process environments by supplying a zone with the controlled particle counts. Esco DPB/DFLH acts as a Material Airlock (MAL) to ensure protection of higher-grade environment by effective flushing with an active filtered air supply as per Revised Annex 1 EU GMP.
Esco DPB/DFLH is the best choice for ensuring your dynamic activities of delivering goods between 2 contrast cleanliness grade areas.
Applications:
Manufacturing Facilities
Pharmaceutical Industry
Cleanroom and Controlled Environments
cGMP facilities
Nanotechnology
Semiconductors Industry
Space Industry
Automotive Industry
Easy to clean construction
Esco DPB/DFLH is constructed from full stainless steel. DPB features cGMP-compliant rounded/coved corners at the base for easy cleaning. While DFLH supplies a floor mounted design for the wheeled cart application.
Cleanliness is assured during the transfer of materials
Equipped with a HEPA (H14) knife-edge gel-sealed main filter and a G4 pre-filter to extend the lifespan of the main filter, providing superior ISO Class 5/Grade A environment within the chamber.
Intuitive user-adaptable controller system
Selection from simple rocker switches or Sentinel™ controller with audio/visual alarms for downflow velocity and filter loading.
Comprehensible signal to indicate the quality of filter
Selection between Magnehelic gauge or digital display of differential pressure value across filters (via SentinelTM Gold microprocessor controller with filter load alarm).
Convenient operation by an identifiable indicator lights
Red/green indicators lights to signal door status and operation status.
Safety-oriented application
The emergency stop button is conveniently positioned on both sides of the unit, ensuring easy accessibility in the event of an unforeseen emergency.
Clear view to the Internal chamber
Esco DPB/DFLH viewing window is constructed with durable tempered glass.
Validated electromagnetic interlocking doors with time-delayed purge
Enhancing safety and Contamination Control Strategy with time-delay air purge and interlocking system that prevent both doors from being opened at the same time.
Optimal air change guarantee to chamber
Safe containment construction allows the optimal air change inside the chamber recirculates via perforated grill system at the side walls.
Adaptable installation with no edge of gap on the wall cut-out
Designed with flanges ensuring smooth and impervious wall-to-pass box finish.
Airflow Regime: Recirculating airflow
Dynamic airflow provides an air barrier to prevent contaminants from entering into critical controlled environments during material transfers
Vertical purging to trace any contaminants that have potentially entered post material transfer.
Unit operates with a recirculating airflow and on-board fans hence, external ducting is not required.
Support stand or Base box
Onboard LED light and/or UV light
Internal shelves
Door release buttons
Interlock release rocker switches
Buzzer system (to alert personnel on the opposite side during material transfer)
Intercom system
Fan fault alarms with customized blowers
Lead shielding
Roller Conveyors (only for DFLH)
Auto sliding PVC doors (only for DFLH)
Rails to hang gowns (only for DFLH)
How do dynamic pass boxes (DPB) differ from dynamic floor laminar hatches (DFLH)?
Our DPB is a wall-mounted unit, featuring coved corners and a 50 mm height base, can be customized with support stands for ergonomic, easy cleaning, and space-saving convenience. In contrast, the DFLH is a floor-mounted unit with a 1.5 mm stainless steel base plate or a floor-finished level (without a base) option, ensuring optimal accessibility for trolley pass-by scenarios.
What is the recommendation of pass box type whether Dynamic Pass Box (DPB) or Static Pass Box (SPB) to transfer material between the same cleanliness grade areas?
For the same cleanliness grade rooms, the most suitable and affordable option is SPB. Moreover, DPB is not limited to the application for material transfer of 2 contrast cleanliness grade areas only. Using DPB for the same cleanliness grade areas will enhance the aseptic transfer environment.
Dynamic pass boxes or dynamic floor laminar hatches (DPB/DFLH) have built in blower and filter and can provide ISO Class 5/ Grade A clean air within the unit.
What airflow pattern does DPB/DFLH operate in?
Standard design of DPB/DFLH runs at a recirculating mode. During operation, room air is drawn to the DPB/DFLH unit and passed through a G3 prefilter, trapping larger particles and increasing the life of the main filter.
Downflow air is then forced evenly through the H14 knife edge gel sealed filter resulting in a unidirectional stream of clean air projected vertically over the internal chamber.
The purified air then recirculates via a G3 prefilter before passing through the H14 filter for downflow supply of air.
Depending on the requirement, it is also possible to design DPB/DFLH to be single pass with air intake and exhaust. This may incur customization costs.
What is the typical efficiency of the filters used for DPB/DFLH?
G4 prefilter with 85% arrestance, and HEPA H14 filter with typical efficiency of >99.995% for particle sizes of 0.3 microns.
How does DPB/DFLH differ from other pass through cabinets offered by Esco?
Esco Pharma has 4 types of pass through cabinets with varying features and capabilities, these include:
Static pass boxes
Esco static pass boxes (EPB-A, EPB-B, SPB) and cleanroom transfer hatches (EPB-S) are situated in between cleanroom or controlled environmentsf to facilitate in the aseptic transfer of material/s in order to mitigate cross-contamination risks.
Dynamic pass boxes and Dynamic Floor Laminar Hatches (DPB/DFLH)
Unlike static ones, DPB/DFLHare aseptic architectural systems which can provide ISO Class 5 as per ISO 14644-1 (Grade A as per EU GMP) environment within the chamber. DPB/DFLH are stand alone units which havebuilt-in pre-filters, HEPA filter and blower integrated within.
Esco air shower pass boxes (EAS-PB)
EAS-PB works similarly to DPB/DFLH whereair is being provided to the internal chamber of the unit except that for EAS-PB, air tis only supplied for a limited duration.
EAS-PB utilizes high velocity air jets which run at 18-30 m/s to provide a “scrubbing” effect to particulate matter or surface contaminants which may potentially be present on the material/s being transferred between rooms.
BioPass™ Pass Through
The design of BioPass™ Pass Through is similar to a dynamic floor laminar hatch (DFLH) wherein both are floor standing units with built in blowers, and is maintained with an ISO Class 5 as per ISO 14644-1 (Grade A as per EU GMP) clean air supply within.
In contrast to the other pass throughs, Biopass™ is integrated with a hydrogen peroxide (H202) based biodecontamination system within and it is designed for r passing through of relativelylarger equipment/ materials into the chamber.
What is the standard operating sequence of DPB/DFLH?
- When one door is opened, the opposite door will be locked (indicator light is red)
- Once the door is closed, both doors will be locked for a specified amount of time to purge potential contaminants that may have leaked into the chamber. (indicator light is red)
- Once the purging time & purging process is done, both doors will remain closed but will be unlocked. Hence, either door is ready to be pulled open. (indicator light is green)
- In case the unit is customized to have an add-on optional door release button, the doors will always be locked. The only time a door can be pulled open is by pressing the door release button first to unlock a door. Once unlocked, only then can the door be pulled open.
